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4.7 out of 5
93.85% of customers are satisfied
5.0 out of 5 stars One of the Best Formulas For MTHFR - Also, Here's Some Other Tips:
Updated as of 10/10/2022:I have known that I have the MTHFR gene mutation for about 12 years now. Even after diagnosis, I was using a few other B-complexes which I though were o.k. for my condition, but I did not realize that the B6 was not methylated. Turns out B6 has to be in the form of Pyridoxal 5-Phosphate, NOT Pyroxidine, to be more bioavailable to those who have MTHFR and do not methylate properly. I never knew that until about 5 years ago; the doctor I tested with didn't explain that part.After this discovery, I researched various B-complex formulas, and picked this one. I also wanted a B-complex that had methylated folic acid and that did not have a super high dose of methylcobalamin (B12), since my blood was testing high for B12 already. This formula fit the bill very well.A few other tips:1) The amount of methylated folic acid per capsule here is low (400mcg). If you only take one capsule per day, I would also recommend taking additional methyl-folate if you do not methylate. However, please first discuss with your chosen physician, if possible.2) If you take B6 in its methylated form of Pyridoxal 5-Phosphate (a.k.a. P5P), you also need to take magnesium so that the P5P pathway will work properly. .Without at least some magnesium to work with, you may end up feeling tired and with lower energy, which is probably not what you want.3) B6 - along with certain co-factors like magnesium, zinc, vitamin-C, and folate, is necessary for the production of certain neurotransmitters like GABA and norepinephrine, as well as for the conversion of tryptophan or 5-HTP into serotonin. So you may want to consider taking some of these additional co-factors to enhance your results with this product (only folate is included in this product, you would have to buy the rest separately). Also note: Tyrosine is also required for the synthesis of dopamine, but I have not tried taking that yet.I believe I have been low in neurotransmitter production, and my nervous system has been a mess, due to a 12-year highly stressful job and the resulting sky-high cortisol levels (Thankfully, I am no longer at that job!). It's been getting better slowly now.....it takes time and it's also very helpful to decrease your sugar and simple carb intake (e.g. white flour).4) B6 and zinc are both needed for the production of pancreatic enzymes and hydrochloric acid, so if you have low stomach acid / poor digestion, this may help. (Zinc is not included in this formula but you may wish to add it if you are looking to help your production of digestive enzymes)In summary, this formula really helps with all the above, and it may help you too. Douglas Labs also makes a similar formula although it has some variation in it's mix. Best wishes to you.Addendum, additional updates since 2017: I had started taking this Thorne Basic B once a day plus an additional 50mg -100mg of P5P back in 2017-2018. Sometimes I would miss a day of both, I'm not perfect :). Eventually I got more disciplined and was taking the Basic B twice a day. I felt that was working better for me. Overall I can say for sure that the combo has helped to calm down my nervous system. I even went through some serious surgeries and medical procedures (extremely stressful) in 2017 and 2018, and in the past I would be a nervous wreck 24/7 and would not be able to calm down. However, I no longer get that uncontrollable anxiety anymore, although there can be some days where I can still fall into a depressive state. Magnesium powder or capsules have also helped keep me calmer (at bedtime), and I have taken some Skullcap, Ashwagandha, and/or Passionflower at times to further calm myself down as needed.Since 2018 I have also tried other methylated B-complex formulas like MethylPro, Douglas Labs, Pure Encapsulations, Nordic Naturals, and Metabolic Maintenance - just to experiment. However I keep returning to this one because it seems to work the best for my physiology. Together with the P5P, this has been like a lifeline for me. I hope it can work for you too if you decide to try it.
5.0 out of 5 stars High quality
We love our Thorne products. We always feel very happy knowing that we are getting high quality supplements. It’s hard to know what you are actually getting from different brands but we feel very satisfied with the work that Thorne does to keep their quality very high!
5.0 out of 5 stars Better than most
No b-burps...gives me healthy energy
5.0 out of 5 stars Thorne is the REAL Vitamin B Complex (Hyperhydrosis)
I had been taking a B Complex supplement made by a known and popular brand.Question: You know when you take a supplement-yet are unsure of it's effects or help your body? That's where I was.A friend recommended Thorne Pharmaceuticals; especially this B Complex. I ordered this and began taking it. My mood has been more even- (I have anxiety and depression.).Another reason for this supplement was experiencing severe craniofacial hyperhydrosis for many years. I looked into potential causes for this condition and found that B12 and/or Folate deficiency could be the culprit. After taking this for 3 days, I experienced something I hadn't for years. My body felt cool. I actually felt cold later that night! I did not realize how poorly my body's temperature regulation had become. I am not getting drenched in awful sweats on a daily basis, as had become my norm. This has been a HUGE help in my life. I can wear make-up again without becoming drenched in eccrine perspiration. My hair would look like I had just run water over it. I could squeeze my hair and have water literally running through my fingers. Embarrassing to say the least; life altering in the negative-absolutely. Not any more. Hyperhydrosis can come from various etiologies- Primary & Secondary. Dermatologists use Botox treatments or prescribe Anti-Cholinergics to treat as I have read.I see myM.D. next week to discuss this, and ask to get Lab work done. I do not know that I have deficiencies, however it seems this may have been the case!Nothing happened with another Brand's B Vits. Read Thorne's label(s). Yes it's more costly than others but it works, and you can feel the difference. I also began supplementing with high dose Vit D3, and take Magnesium Citrate. Remember that D3 needs a fat to work properly, so take with avocado, or your morning meal? (I am 65, female and do not eat much meat.). Hope this might help someone.
4.0 out of 5 stars Great… but where’s the allithiamine?
Allithiamine is the natural form of B1, and is fat soluble rather than water soluble like its counterpart, thiamine. It would be great as the fat soluble has better long term effects on the brain. Other than that, it’s a great B complex. Just could be a tad better.
5.0 out of 5 stars One a day
very strong just need one a day to give you all the B vitamins you neeed
5.0 out of 5 stars Works Great!
This pill works great, was easy to swallow and doesn't have a weird aftertaste like many of them!
5.0 out of 5 stars Great B Complex
My son and I both take this B complex. It helps reduce numbness in out feet and hands.
Producto increíble!
Producto increible!
活性化ビタミンBコンプ
某巨大掲示板で見かけたので興味本位で購入いたしました。効果あります!身体が軽く疲れにくくなって驚きました♡あと、化粧ノリ抜群です!!!
Recomendado por mi naturópata
Es muy difícil de saber si el producto es útil o no porque tomo varios productos recomendado por mi naturópata
Es un buen producto, pero falta información
Este producto es de los mejores que hay, investigué mucho antes de comprar un complejo de vitamina B. Tiene los tipos de vitaminas b de mejor cailidad. (methylcobalamin entre otros) Se asimila muy bien.El problema es que es muy potente y si eres sensible puedes tener efectos adversos como pesadillas, insomnio, ansiedad, empezar a rechinar los dientes por la noche y acabar con sensación de agotamiento.Empecé tomando solo la mitad y lo tomé tres días, y cada noche fue peor; tuve fuertes pesadillas muy reales, me despertada en tensión y daba vueltas sin parar y no descansaba bien ni suficiente.Buscando otras experiencias similares para ver que estaba ocurriendo, he descubierto que muchas personas tienen este problema.Ojalá lo hubiera sabido antes.Deberían informar mejor sobre los posibles efectos adversos y dosificaciones.Es un tema complicado y cada marca pone unas cantidades diferentes.Dependiendo de tu capacidad de absorción y sensibilidad este producto puede ayudarte o puede estimularte demasiado.
Good
Using it now for long time, i had no side effects.
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Product origin: United States
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